Contact Info
Education
Ph.D. in Physical Chemistry, Seoul National University, Korea, 2009
Dissertation Topic: Biological Application of Alternating Laser EXcitation (ALEX) and Total Internal Reflection Fluorescence (TIRF) Technique
Area of Study: Fluorescence spectroscopy and imaging, single-molecule biophysics
B.S. in Chemistry, Seoul National University, Korea, 2002
Experience
2016.01. ~ 2017.02. Research scientist in Department of Biophysics, Johns Hopkins University, USA
2015.04. ~ 2015.12. Postdoctoral research associate in Department of Bioengineering, University of Illinois at Urbana-Champaign, USA 
2010.05. ~ 2015.03. Postdoctoral research associate in Department of Physics, University of Illinois at Urbana-Champaign, USA
2009.03. ~ 2010. 04. Postdoctoral research associate in Department of Chemistry, Seoul National University, Korea 
Research Interests

• Molecular mechanisms of RNA-mediated gene regulation at the single-molecule level

• Quantitative analysis of the interplay between transcription and RNA splicing

• Subcellular localization and quantification of diseases-related genes at the single-cell level

• Development of a cutting-edge technique complementing current sequencing methods in RNA biology and its application to cancer diagnosis

Selected Publications

1. H. R. Koh, M. A. Kidwell, J. A. Doudna and S. Myong, “RNA Scanning of a Molecular Machine with a Built-in Ruler”, J. Am. Chem. Soc. 139, 262-268 (2017)

2. H. R. Koh, X. Wang and S. Myong, “Visualizing repetitive diffusion activity of double-strand RNA binding proteins by single molecule fluorescence assays”, Methods (2016)

3. H. R. Koh, L. Xing, L. Kleiman and S. Myong, “Repetitive RNA unwinding by RNA helicase A facilitates RNA annealing”, Nucleic Acids Res. 42, 8556-8564 (2014) 

4. Y. Qiu, E. Antony, S. Doganay, H.R.Koh, T. M. Lohman and S. Myong, “Srs2 prevents Rad51 filament formation by repetitive scrunching of DNA”, Nat. Commun. 4, 1-10 (2013) 

5. H. R. Koh, M. A. Kidwell, K. Ragunathan, J. A. Doudna and S. Myong, “ATP-independent diffusion of double-stranded RNA binding proteins”, Proc. Nat’l Acad. Sci. U.S.A. 110, 151-156 (2013)